Negative Regulation of TSC1-TSC2 by Mammalian D-Type Cyclins
نویسندگان
چکیده
منابع مشابه
Negative regulation of TSC1-TSC2 by mammalian D-type cyclins.
The metazoan cell cycle is driven by the timely and composite activities of cyclin-dependent kinases (CDKs). Among these, cyclin D- and cyclin E-dependent kinases phosphorylate the pRb family proteins during G(1) phase of the cell cycle and thereby advance cells beyond the restriction point. Increasing evidence suggests that cyclin D-dependent kinases might affect events other than Rb pathway-m...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2005
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-05-2236